Instruments & Rates

All rates are:

  • per sample if run by MSF personnel.
  • per sample if run by users on the Agilent GC-MS.
  • per hour if run by user on the Bruker UltrafleXreme MALDI (with a minimum charge of 1 hour), and the Advion CMS (with a minimum charge of 10 minutes).
  • Per hour of gradient on the Q-Exactive (with a minimum charge of 1 hour)

Please note that you can get access to the user rates even if the MSF is running the samples by provide "ready to run" samples and analyze the raw data on your own.

 

Agilent 6230 ESI TOF

ESI TOF instrument

ESI TOF source

ESI TOF LC

ESI TOF Sampler

The Agilent ESI TOF 6230 is an exact mass LC equipped mass spectrometer capable of > 10,000 resolution, 2 ppm mass accuracy and sensitivity as low as 1 pg per injection. Analysis can be performed using either of the two available sources: electrospray ionization with Agilent Jet Stream ESI source or Multimode Source (ESI/APcI). Samples can be introduced into the instrument with either direct injection for purified samples or through an LC column for further separation. The instrument provides mass analysis and mass validation in support of organic, inorganic and biological compounds. 

Technique LSU Campus Academic Outside LSU Industry
ESI-TOF Flow-through (Staff run) 21 28 120
ESI-TOF LC (Staff run) 31 41 120
ESI-TOF Flow-through (User run) 16 N/A N/A
ESI-TOF LC (User run) 26 N/A N/A

 

Bruker UltrafleXreme MALDI TOF/TOF

MALDI imaging

MALDI Bruker ultrafextreme instrument

Bruker UltrafleXreme MALDI TOF

Bruker UltrafleXreme MALDI TOF

The Bruker MALDI TOF/TOF mass spectrometer was funded in 2009 through a NIH shared instrument grant. The instrument is a state of the art device capable of 40,000 mass resolution and 1 ppm mass accuracy. It can be loaded with 384 well sample targets suitable for high throughput analysis. The instrument is specifically designed for mass spectrometry imaging thanks to its 1 KHz laser which can be focused at 10 μm spot size. In addition, the instrument has an innovative ultrafast detector, which can acquire spectra at 2 Giga sample per second, allowing acquisition of mass spectrometry images of surfaces at its maximum mass resolution. The instrument is used for both fast and accurate determination of synthetic and biological organic compounds as well as for biological mass spectrometry imaging of tissue samples.

Technique LSU Campus Academic Outside LSU Industry
MALDI (Staff run) 29 39 120
MALDI (User run) 24 N/A N/A
MALDI MS/MS (Staff run) 54 73 120
MALDI MS/MS (User run) 54 N/A N/A
MALDI Imaging (Staff run) 54 73 120
MALDI Imaging (User run) 54 N/A N/A

 

Bruker Amazon Speed ETD Ion Trap

Bruker Amazon

Bruker Amazon Source

Bruker Amazon Inlet

Amazon computer data

This ion trap mass spectrometer is among the fastest on the market. It can be equipped with an ESI ion source or a Captive Spray ion source for nanospray analysis at increased sensitivity. The mass spectrometer is coupled to a Dionex Ultimate 3000 LC system. The system is mainly used for fast chromatography MS and tandem MS analysis, with a focus on small molecules quantification and protein MW determination.

Technique LSU Campus Academic Outside LSU Industry
IT-LC-MS (Staff run) 29 39 120
IT-LC-MS/MS (Staff run) 45 60 120
IT-MS Flow-through (Staff run) 19 25 120
IT-MS Intact protein (Staff run) 24 32 120
IT-LC-MS (User run) 24 N/A N/A
IT-LC-MS/MS (User run) 40 N/A N/A
IT-MS Flow-through (User run) 14 N/A N/A
IT-MS Intact protein (User run) 19 N/A N/A

 

GC-MS

Through a collaboration with the teaching units of the Chemistry department the MSF offers also GC-MS single quad analysis capabilities. Please contact us for more information.

Technique LSU Campus Academic Outside LSU Industry
GC-MS (Staff run) 16 21 44
GCMS (User Run) 14 N/A N/A

 

Thermo Scientific Q-Exactive

Q-Exactive Instrument

Q-Exactive Source

Q-Exactive Inlet

Q-Exactive Instrument

The Thermo Scientific Q-Exactive mass spectrometer is coupled to a Thermo Scientific Ultimate 3000 RSLC nanoLC system and it is dedicated to bottom up proteomics. Samples that can be analyzed with this system range from single protein gel band to complex cell and tissue lysates.

To provide accessible rates for complex proteomics experiments, we build sample preparation kits tailored to the specific needs of the experiment. Please contat us to discuss your experiment and we will provide estimates based on the specific details of your research.

Technique LSU Campus Academic Outside LSU Industry
Proteomics LC 40 60 120
Intact protein flow-through 32 43 120

Advion CMS platform with PlateExpress TLC reader 

Advion CMS

Advion PlateReader

Advion APCI Source

Advion ESI Source

The Advion CMS system is a multisource platform that include a TLC extraction plate, thus making it the ideal solution for quick characterization of complex organic mixtures. The availability of ESI, APCI, and ASAP ionization makes it possible to ionize a broad range of chemicals in conditions that other instrument are not able to accomodate (e.g., high amount of organic solvents such as ethylacetate or dichloromethane). This instrument allows extraction of a spot from a TLC plate, which is a unique feature of this platform.

 

Technique LSU Campus Academic Outside LSU Industry
Advion Expression (Staff run) 4 N/A N/A
Advion Expression (user run) 4 N/A N/A

Other MS services

The LSU MSF offers data analysis and sample preparation services such as buffer exchange, proteomics sample preparation, SPE purification and others. Further details and exact costs of each kit can be requested using the "Contact us" link above.

Technique LSU Campus Academic Oustide LSU Industry
Data analysis 45 45 45
Special Analysis Cost of kit
+ instrument charge
Cost of kit
+ instrument charge
Cost of kit
+ instrument charge
Method development 50 50 50