Education

Post-doctoral fellowship, Louisiana State University

PhD, Freie Universitat Berlin (Germany)

MVSc, ICAR-Indian Veterinary Research Institute (India)

BVSc & AH, Tamil Nadu Veterinary and Animal Sciences University (India)

Research Interest

I am a trained veterinarian, pathologist, and molecular virologist. My research project involves developing novel animal herpesvirus vectored vaccines against other bovine and swine viral diseases.  My current research interests are i) Studying the molecular basis of Alphaherpesvirus pathogenesis using bovine herpesvirus 1 and its natural host, cattle, as a surrogate model, ii) Developing animal herpesvirus vectored vaccines against other viral infections in cattle, sheep, pigs, and horses. Besides my research goals, I am also passionate about educating future veterinarians and training graduate students.  

Teaching Interest

Molecular Virology, Pathogenic Mechanism of Viral Diseases  

Awards & Honors

2022, Best Poster presentation Award, Society of Phi Zeta, LSU School of Veterinary Medicine, USA

2019, International Herpesvirus Workshop Merit Award, USA

2018, ZIBI best poster presentation Award, Germany

2018, An honorarium of C$500 in Calgary International Equine Symposium, Canada

2016-19, Netaji Subhas-ICAR International Fellowship Award-2015-16 from Govt. of India (Honor of ICAR-international fellow 2016-2019 with $75,000 fellowship)

2015, Young Scientist Award, Indian Association of Veterinary Pathologist, India

2015, Dr. Ram Raksha-Kiran Shukla Best MVSc thesis Award, Indian Association of Veterinary Pathologist, India

2012-14, ICAR-Indian Veterinary Research Institute Fellowship Award, India

Patents Filed

2021, A modified vaccine construct for EHV1 and methods of preparing the same. Indian Patent office, Delhi, India.

2021, Monoclonal antibody-based immunoassay for detection of equine influenza (H3N8) antigen. Indian Patent office, Delhi, India.

2021, Mutated EHV1 genome-based vaccine construct and method for preparation. Indian Patent office, Delhi, India.

Selected Publications

2022, Pavulraj, S.; Pannhorst, K.; Stout, R.W.; Paulsen, D.B.; Carossino, M.; Meyer, D.; Becher, P.; Chowdhury, S.I. A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV. Vaccines (Basel), 10, doi:10.3390/vaccines10020305.

2021, Pavulraj, S.; Bergmann, T.; Trombetta, C.M.; Marchi, S.; Montomoli, E.; Alami, S.S.E.; Ragni-Alunni, R.; Osterrieder, N.; Azab, W. Immunogenicity of Calvenza-03 EIV/EHV((R)) Vaccine in Horses: Comparative In Vivo Study. Vaccines (Basel), 9, doi:10.3390/vaccines9020166.

2021, Pavulraj, S.; Eschke, K.; Theisen, J.; Westhoff, S.; Reimers, G.; Andreotti, S.; Osterrieder, N.; Azab, W. Equine Herpesvirus Type 4 (EHV-4) Outbreak in Germany: Virological, Serological, and Molecular Investigations. Pathogens, 10, doi:10.3390/pathogens10070810.

2021, Chowdhury, S.I.; Pannhorst, K.; Sangewar, N.; Pavulraj, S.; Wen, X.; Stout, R.W.; Mwangi, W.; Paulsen, D.B. BoHV-1-Vectored BVDV-2 Subunit Vaccine Induces BVDV Cross-Reactive Cellular Immune Responses and Protects against BVDV-2 Challenge. Vaccines (Basel), 9, doi:10.3390/vaccines9010046.

2020, Pavulraj, S.; Kamel, M.; Stephanowitz, H.; Liu, F.; Plendl, J.; Osterrieder, N.; Azab, W. Equine Herpesvirus Type 1 Modulates Cytokine and Chemokine Profiles of Mononuclear Cells for Efficient Dissemination to Target Organs. Viruses, 12, doi:10.3390/v12090999.

2020, Kamel, M.; Pavulraj, S.; Fauler, B.; Mielke, T.; Azab, W. Equid Herpesvirus-1 Exploits the Extracellular Matrix of Mononuclear Cells to Ensure Transport to Target Cells. iScience, 23, 101615, doi:10.1016/j.isci.2020.101615.

2019, Pavulraj, S.; Eschke, K.; Prahl, A.; Flugger, M.; Trimpert, J.; van den Doel, P.B.; Andreotti, S.; Kaessmeyer, S.; Osterrieder, N.; Azab, W. Fatal Elephant Endotheliotropic Herpesvirus Infection of Two Young Asian Elephants. Microorganisms, 7, doi:10.3390/microorganisms7100396.

2019, Pavulraj, S.; Kamel, M.; Osterrieder, K.; Azab, W. EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives. Front Vet Sci, 6, 251, doi:10.3389/fvets.2019.00251.

2017, Pavulraj, S.; Virmani, N.; Bera, B.C.; Joshi, A.; Anand, T.; Virmani, M.; Singh, R.; Singh, R.K.; Tripathi, B.N. Immunogenicity and protective efficacy of inactivated equine influenza (H3N8) virus vaccine in murine model. Vet Microbiol, 210, 188-196, doi:10.1016/j.vetmic.2017.08.013.

2015, Pavulraj, S.; Bera, B.C.; Joshi, A.; Anand, T.; Virmani, M.; Vaid, R.K.; Shanmugasundaram, K.; Gulati, B.R.; Rajukumar, K.; Singh, R., et al. Pathology of Equine Influenza virus (H3N8) in Murine Model. PLoS One, 10, e0143094, doi:10.1371/journal.pone.0143094.

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