Sara Lyle

Sara K. Lyle

Associate Professor of Theriogenology

Department of Veterinary Clinical Sciences

LSU School of Veterinary Medicine
Louisiana State University
Baton Rouge, LA 70803

EMAIL DR. LYLE

Education

PhD, LSU, 2008

MS, University of Florida, 1991

DVM, University of Florida, 1985

Certifications

Diplomate, American College of Theriogenology

Research Interest

  • Equine endometritis & placentitis
  • Biofilm of the urogenital tract (equine and canine)
  • Non-invasive models for reproductive research

Teaching Interest

New models for theriogenology clinical procedures

Clinical Interest

Broodmare infertility

Awards

2014, 2013, 2012, Dean's Teacher Merit Honor Roll, LSU Vet Med

1990 Phiu Zeta Award for Research Achievement

1985, Charles E. Bild Clinical Proficiency Award, Florida Veterinary Medical Association

Publications

Macpherson ML, Giguère S, Pozor MA, Burden CA, Berghaus LJ, Berghaus RD, Varner JC, Hayna JT, Benson SM, Randell SA, Lyle SK, Kelleman AA, Hart KA, Mallicote MF, Horohov DW.Am J Reprod Immunol. 2021 Jul;86(1):e13396. doi: 10.1111/aji.13396. Epub 2021 Feb 10.PMID: 33569862

Metabolomic Profile of Allantoic and Amniotic Fluid in Late-term Gestational Mares Characterized by 1H-nuclear Magnetic Resonance Spectroscopy.

Beachler TM, Scott Bailey C, Gracz HS, Morgan DR, Von Dollen KA, Ellis KE, Gadsby JE, Lyle SK.J Equine Vet Sci. 2020 Nov;94:103235. doi: 10.1016/j.jevs.2020.103235. Epub 2020 Aug 25.PMID: 33077068 Plasma metabolomic profiling of healthy pregnant mares and mares with experimentally induced placentitis.

Beachler TM, Gracz HS, Morgan DR, Bembenek Bailey SA, Borst L, Ellis KE, Von Dollen KA, Lyle SK, Nebel A, Andrews NC, Koipalli J, Gadsby JE, Bailey CS.Equine Vet J. 2021 Jan;53(1):85-93. doi: 10.1111/evj.13262. Epub 2020 Apr 15.PMID: 32187705 Antimicrobial Activity of Ceftiofur and Penicillin With Gentamicin Against Escherichia coli and Streptococcus equi Subspecies zooepidemicus in an Ex Vivo Model of Equine Postpartum Uterine Disease.

Von Dollen KA, Jones M, Beachler T, Harris TL, Papich MG, Lyle SK, Bailey CS.J Equine Vet Sci. 2019 Aug;79:121-126. doi: 10.1016/j.jevs.2019.06.005. Epub 2019 Jun 20.PMID: 31405490 Pharmacokinetics of Intrarectal Altrenogest in Horses.

Ellis KE, Council-Troche RM, Von Dollen KA, Beachler TM, Bailey CS, Davis JL, Lyle SK.J Equine Vet Sci. 2019 Jan;72:41-46. doi: 10.1016/j.jevs.2018.10.001. Epub 2018 Oct 10.PMID: 30929782 Sperm quality during extra-gonadal sperm reserve depletion in stallions.

Len JA, Beehan D, Eilts B, Lyle SK.Reprod Domest Anim. 2019 Feb;54(2):412-414. doi: 10.1111/rda.13359. Epub 2018 Nov 8.PMID: 30315666 Characteristics of Dogs with Biofilm-Forming Escherichia Coli Urinary Tract Infections.

Kern ZT, Jacob ME, Gilbertie JM, Vaden SL, Lyle SK. J Vet Intern Med. 2018 Sep;32(5):1645-1651. doi: 10.1111/jvim.15231. Epub 2018 Aug 7.PMID: 30084122 Free PMC article. Immunology of infective preterm delivery in the mare.

Lyle SK. Equine Vet J. 2014 Nov;46(6):661-8. doi: 10.1111/evj.12243. Epub 2014 Mar 21.PMID: 24552615 Review.

Grant Funding

2023 Lyle SK, Len JA, Breen M. American Kennel Club-Canine Health Foundation, Inc. Theriogenology Residency – NCSU. (Transferred to LSU) $125,000. July 2024 – June 2026.

2020 Lyle SK, Nebel A. Papich M. NCSU CVM Intramural Research Funds. Pharmacokinetics of Intravenous Carprofen in Canine Lactation.

2018 Adin CA, Lyle SK. Contraline, LLC. Non-GLP Proof-of-Concept Study: Evaluating the Safety of Efficacy of Echo-VRTM Model System, $65,163. March 2018 to October 2018. Co-investigator. $8,500. June 2021 to July 2022.

2017 Bailey CS, Beachler T, Lyle SK, Gadsby J, Jones S, Gracz H. Grayson Jockey Club Foundation. Metabolomic profiling of placentitis biomarkers in mares. $90,453, April 2017 to April 2018. Co-investigator.

2016 Bailey CS, Lyle SK. American Kennel Club-Canine Health Foundation, Inc. Theriogenology Residency – NCSU. $100,000. July 2016 to June 2019.

2016 Adin C, Lyle SK. Contraline LLC. Canine cadaver model for vasinotomy. $37,663, October 2016 to August 2017. Co-investigator.

2015 Gauthier TJ, Lyle SK, Paccamonti, DL. US Department of Interior Bureau of Land Management: Wild Horse and Burro Program. The use of membrane disrupting peptide/peptoid LHRH conjugates to control wild horse and burro populations. $1,120,741, January 2015 to December 2017. Co-investigator.