Joyoni Deydey

Assistant Professor

Ph.D. in Electrical and Computer Engineering, 1999 - Carnegie Mellon University

Louisiana State University
Department of Physics & Astronomy
459-A Nicholson Hall, Tower Dr.
Baton Rouge, LA 70803-4001
(225) 578-4289-Office
(225) 578-9048-Lab
deyj@lsu.edu

Teaching

Fall:         MedP 7111: Advanced Medical Imaging Physics

Spring:    MedP 4111: Introduction to Medical Imaging

Spring:    (Co-Instructor): Radiological Physics for Residents (LSU Health Sc)

Research

Expertise in medical imaging and image processing, particularly imaging system design and optimization, reconstruction with physical modeling, mathematical modeling for quantification, segmentation and registration. My research focuses on new systems and algorithms designed to help large patient populations with new imaging advances: for example, higher resolution,  higher sensitive systems for better quality diagnostic images, more efficient acquisition, lower dose requirement etc.; pathological quantification algorithms; correction of motion artifacts for better diagnosis.

Current Projects Include

System Design and Optimization

  • Optimizing a Novel Gamma Camera design for Cardiac SPECT: We are investigating a high-sensitive and/or high-resolution gamma-camera design with a system of Ellipsoid detectors with pinhole collimation for Cardiac SPECT, which is an important modality for assessing myocardial perfusion with millions of patients undergoing nuclear cardiology scans per year. In course of our research, we have built a comprehensive multi-pinhole system simulator and iterative reconstruction.

           Example Relevant Publications/Patents/Disclosures

          J. Dey and S.J. Glick, "SPECT Camera Design", Patent No., US 8,519,351 B2, Aug 27, 2013

          J. Dey, “Improvement of Performance of Cardiac SPECT Camera using Curved Detectors With Pinholes”, IEEE Trans. Nuclear Science, vol.59, no.2,pp.334-347, April 2012

  • Phase-Contrast X-ray not only provides attenuation images provided by conventional CT but also scatter and phase images, affording higher soft-tissue contrast in images compared to conventional CT. We are investigating a novel single grating far-field system to bring Phase Contrast X-ray a step closer to the clinic. In collaboration with Professor Les Butler (Dept of Chemistry), Dr. Kyungmin Ham (CAMD) and Dr. Jonathan Dowling (Dept of Physics).

    Example Relevant Publications/Patents/Disclosures

    J. Xu, J. Dey, N. Bhusal, et al., “Two-dimensional Linear Quadratic Grating for X-ray Interferometry”, accepted SPIE Medical Imaging, 2018  (oral)

    J. Dey, J. Xu, N. Bhusal, , K. Ham, , V. Singh, “A Novel Phase Contrast System”,  presented, IEEE NSS-MIC, Oct 2017 (oral)

           J. Dey, et. al., "Phase Contrast X-ray Interferometry," Provisional Patent July 24, 2017

Building Bioanalytical Tools using Mathematical Models:

  • Tumor progress and disease treatment monitoring by extracting biophysical-model-parameters from images: Oncology Imaging is performed using modalities including CT, MRI, FDG-PET, SPECT etc. Applying realistic mathematical models to serial-images of tumors extracts biologically relevant information from images, such as cell-motility, growth-rate etc. We are investigating a new mathematical Finite Element tumor-model where effects of the necrotic core are considered in addition to cell-motility, growth, apoptosis and migration. We also acquired 6 preclinical serial SPECT/CT datasets and fitted an existing ode compartmental volume model. In collaboration with J. M. Mathis, PhD, (Dept of Comparative Biomedical Sciences, School of Vet Medicine, LSU) and S. W. Walker, PhD (Dept of Mathematics, LSU).

          Example Relevant Publications/Patents/Disclosures

           I. Hidrovo, J. Dey, M. E. Chesal, D. Shumilov, N. Bhusal and J. M. Mathis, "Experimental Method and Statistical Analysis to Fit Tumor Growth Model Using SPECT/CT Imaging: A                  Preclinical Study", Quant Imaging in Med and Surg,  vol. 7, no. 3, pp. 299-309, June 2017,doi: 10.21037/qims.2017.06.05
 
          J. Dey, S. W. Walker, J. M. Mathis, D. Shumilov, K. M. Kirby and Y. Luo, "Modeling and analysis of a physical tumor model including the effects of necrotic core," in Proc 2015 IEEE               Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), San Diego, CA, 2015, pp. 1-4.
 
  • Fat-mass and Lean-Mass Growth Models: Mathematical modeling of fat-mass and lean-mass growth upon overfeeding different diets (collaboration with S. Heymsfield, MD, and L. M. Redman, PhD, from Pennington Biomedical Research Center).

    Example Relevant Publications/Patents/Disclosures

    D. Shumilov, S. B. Heymsfield, Leanne M. Redman, Steven R. Smith, George A. Bray, K. Kalluri, J. Dey, “New Compartment Model Analysis of Lean-Mass and Fat-Mass Growth with Overfeeding”, Nutrition, vol. 32, no. 5, pp. 590-600, May 2016

Patents

          J. Dey and S.J. Glick, "SPECT Camera Design", Patent No., US 8,519,351 B2, Aug 27, 2013

Students

Ph.D.

  • Jingzhu Xu

MSc

  • Narayan Bhusal

Undergraduate

  • Ivan Hidrovo (REU, Summer 2016, Summer 2017, Acad year 2017-2018)
  • Megan E. Chesal (Spring 2016, Acad year 2017-2018)
  • David Sanchez (REU, Summer 2017)

Publications

Selected Peer-Reviewed Journal Papers

  • I. Hidrovo, J. Dey, M. E. Chesal, D. Shumilov, N. Bhusal and J. M. Mathis, "Experimental Method and Statistical Analysis to Fit Tumor Growth Model Using SPECT/CT Imaging: A Preclinical Study", Quantitative Imaging in Med and Surg, vol. 7, no. 3, pp. 299-309, June 2017,doi: 10.21037/qims.2017.06.05
  • D. Shumilov, S. B. Heymsfield, Leanne M. Redman, K. Kalluri, J. Dey, "New Compartment Model Analysis of Lean-Mass and Fat-Mass Growth with Overfeeding", Nutrition, vol. 32, no. 5, pp. 590-600, May 2016
  • C. Chan, J. Dey, Y. Grobshtein, J. Wu, Y-H Liu, R. Lampert, A. J. Sinusas, C. Liu, “The Impact of the Dimension of System Matrix and Object Support in Reconstruction for a Stationary Dedicated Cardiac SPECT with Truncated Projections”, Medical Physics, vol. 40, no. 1, pp. 213-224, Jan 2016
  • M. A King, J. M. Mukherjee, A. Konik, I.Zubal, J. Dey, R. Licho, “Design of a Multi-Pinhole Collimator for I-123 DaTscan Imaging on Dual-Headed SPECT Systems in Combination with a Fan-Beam Collimator”,  IEEE Trans. Nuclear Science, vol. 63, no. 1, pp. 90-97, Feb 2016
  • M. Smyczynski, H. Gifford, J. Dey, A. Lehovich, J. McNamara,  P. Segars, M. A. King, “LROC Investigation of Three Strategies for Reducing the Impact of Respiratory Motion on the Detection of Solitary Pulmonary Nodules in SPECT”, IEEE Trans. Nuclear Science, vol. 63, no. 1, pp. 130-139, Feb 2016
  • J. Dey, W. P. Segars, P. H. Pretorius, and M. A. King, “Effect of Non-Alignment/Alignment of Attenuation Map Without/With Emission Motion Correction in Cardiac SPECT/CT”, IEEE Trans. Nuclear Science, vol. 62, no. 4, pp. 1813-24, Aug 2015
  • A.Konik, C. Connolly, K. L. Johnson, P. Dasari, P. Segars, P. H. Pretorius, C. Lindsay, J. Dey, M. A. King, “Digital Anthropomorphic Phantoms of Non-Rigid Human Respiratory and Voluntary Body Motion for Investigating Motion Correction in Emission Imaging", Physics in Medicine and Biology vol. 59, no. 14, pp. 3669-82, July 2014
  • P. Dasari, K. L. Johnson, J. Dey, C. Lindsay, M.S. Shazeeb, J. M. Mukherjee, S. Zheng, and M. A. King, "MRI Investigation of the Linkage Between Respiratory Motion of the Heart and Markers on Patient’s Abdomen and Chest: Implications for Respiratory Amplitude Binning List-Mode PET and SPECT Studies", IEEE Trans Nuclear Science, vol. 61, no.1, pp. 192- 201, Feb 2014
  • M. A. King, J. Dey, K. L. Johnson, P. Dasari, J. M. Mukherjee, J. E. McNamara, A. Konik, C. Lindsay, S. Zheng, and D. Coughlin, “Use of MRI to assess the prediction of heart motion with gross body motion in myocardial perfusion imaging by stereo-tracking of markers on the body surface”, Medical Physics, vol. 40, no. 11, pp. 112504-1-14, Nov 2013
  • M. Jin, X. Niu, W. Qi, Y. Yang, J. Dey, M. A. King, S. Dahlberg, and M.N.Wernick, “4D Reconstruction For Low-Dose Cardiac Gated SPECT”,Medical Physics, vol. 40, no. 2, pp. 022501-1-12, Feb 2013
  • J. Dey, “Improvement of Performance of Cardiac SPECT Camera using Curved Detectors With Pinholes”, IEEE Trans. Nuclear Science, vol.59, no.2,pp.334-347, April 2012
  • J. Dey, W. P. Segars, R. P. Walvick, P. P. Bruyant, P. H. Pretorius, S. Dahlberg, and M. A. King, “Estimation and Correction of Cardiac Respiratory Motion in Presence of Limited Angle Effects due to Irregular Respiration in SPECT”, Medical Physics, vol. 37, no. 12, pp. 6453-6465, Dec 2010
  • J. Dey, T. Pan, D.J.Choi, D. Robotis, M. S.Smyczynski, P.H. Pretorius, M.A. King, “Estimation of Cardiac Respiratory-Motion by Semi-automatic Segmentation and Registration of Non-Contrast-Enhanced 4D-CT Cardiac Datasets”, IEEE Trans Nuclear Science, IEEE Trans. Nuclear Science,vol. 56, no. 6, pp. 3662-3671, Dec 2009
  • J. Dey, M.A. King, “Theoretical and Numerical Study of MLEM and OSEM Reconstruction Algorithms for Motion Correction in Emission Tomography”, IEEE Trans Nuclear Science, vol. 56, no.5, pp. 2739- 2749, Oct 2009
  • J. E. McNamara, P.H. Pretorius, K. Johnson, J. Mitra, J. Dey, M. A. Gennert, M. A. King, “A Flexible Multi-camera Visual-tracking System for Detecting and Correcting Motion-induced Artifacts in Cardiac SPECT Slices”, Medical Physics, vol. 36, no. 5, pp. 1913-1923, May 2009
  • J. Mitra, J. McNamara, K. Johnson, J. Dey, M. A. King, “Estimation of Rigid-body and Respiratory Motion of the Heart From Marker-Tracking Data for SPECT Motion Correction”, IEEE Trans Nuclear Science, vol. 56, no.1, pp. 147-155, Feb 2009
  • J. Dey and S. Napel, "Targeted 2D/3D registration using a hybrid optimizer and normalization of rays", Medical Physics, vol. 33, no. 12, pp. 4730-4738, Dec 2006
  • B. Feng, P. P. Bruyant, P. H. Pretorius, R. D. Beach, H. C. Gifford, J. Dey, M. Gennert, M. A. King "Estimation of the Rigid-Body Motion from Three-Dimensional Images Using a Generalized Center-of-Mass Points Approach", IEEE Trans on Nuclear Science, vol. 53, no. 5, pp. 2712-2718, Oct 2006
  • D. S. Paik, C. F. Beaulieu, G. D. Rubin, B. Acar, R. B. Jeffrey, Jr., J. Yee, J. Dey, S. Napel, "Surface Normal Overlap: A Computer-Aided Detection Algorithm With Application to Colonic Polyps and Lung Nodules in Helical CT", IEEE Transactions on Medical Imaging, vol. 23, no. 6, pp. 661-675, June 2004

Selected Peer-Reviewed Conference Publications

  • J.Dey, Y. Wu, X. Wu, M. Xia, Z. Yan, E. Stefani, and Y-H. Xie, "Penalized Maximum Likelihood Iterative Reconstruction for Sub-wavelength Nano-scale Optical Computed Tomography (SNOCT) for Isolated Cell Imaging", presented 12th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine (Fully 3D), Lake Tahoe, CA, June 2013.
  • J.Dey, R. Licho, "Toward improved quantification of disease progression and treatment monitoring using dynamic or static steady-state tumor-model parameters", in Proc.of 2013 SPIE , Medical Imaging 2013: Digital Pathology, vol. 8676, pp. 867609-1-10, Feb 2013, (oral)
  • J. M. Mukherjee, J.Dey, M.A. King, S. Konate,”Objective assessment of penalized maximum likelihood reconstruction with sparsity-promoting penalty for Myocardial perfusion SPECT imaging”, in Proc.of 2013 SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, vol. 8668, pp. 86681Y-1-8, Feb 2013
  • C.M. Connolly, A. Konik, P.K.R. Dasari, P. Segars, S. Zheng, K.L. Johnson, J. Dey, M.A. King, “Creation of 3D Digital Anthropomorphic Phantoms which Model Actual Patient Non-rigid Body Motion as Determined from MRI and Position Tracking Studies of Volunteers”, in Proc of2011 SPIE, Medical Imaging, Visualization, Image-Guided Procedures, and Modeling, vol. 7964, pp79642G-1-8, Feb 2011
  • J. Dey, J. M. O'Connor, Y. Chen, S. J. Glick, "Temporal change analysis for improved tumor detection in dedicated CT breast imaging using affine and free-form deformation." in Proc of 2008 SPIE, Medical Imaging, Physics of Medical Imaging, vol. 69131 pp. 69131D-1 -10, Feb 2008, (oral)
  • J. Dey, T. Pan, D. J. Choi, M. Smyczynski, P. H. Pretorius, M. A. King,  "Knowledge-based segmentation of the heart from respiratory-gated CT datasets acquired without cardiac contrast-enhancement", in Proc. of the 2006 SPIE, Medical Imaging,(Image Processing) vol. 6144, pp. 77-84 Feb 2006, (oral)
  • J. Dey, D. A. Tighe, G. Vijayaraghavan, V. Mitra, P. Pedersen, "Prior-shape based segmentation of various objects in ultrasound images after speckle-reduction using level-set based curvature evolution", in Proc. of the 2006 SPIE, Medical Imaging, (Image Processing) vol. 6144, pp.1515-1523, vol. 6144, Feb 2006
  • P. C. Pedersen, V. Mitra, J. Dey, "Boundary detection in 3D ultrasound reconstruction using nearest neighbor map", in Proc. of the 2006 SPIE, Medical Imaging, vol. 6147, pp. 57-67, Feb 2006
  • J. Dey, B. Feng, K. L. Johnson, J. E. McNamara, P. H. Pretorius, M. A. King, "Respiratory Motion Correction in Cardiac SPECT using Affine and Free-Form Registration with Temporal and Spatial Constraints",(Oral) the 9th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine (Fully 3D) July, 2007
  • J. Dey and T. Kanade, "Modeling and analysis of ultrasonic echoes reflected from a surface under two layers". In Proceedings of Third International Conference on Medical Image Computing and Computer -Assisted Intervention (MICCAI 2000), Lecture Notes in Computer Science, vol. 1935, Springer, Pg. 482-492, 2000

 

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