SPRING SEMINAR SERIES
Comparative Biomedical Sciences
School of Veterinary Medicine
Room 1212C - 12 Noon
February 22, 2018
Judith T. Zelikoff, PhD
Laboratory of Pulmonary & Systemic Toxicology
New York University School of Medicine
Host: Dr. Alexandra Noël
“Electronic cigarettes and pregnancy: Lessons learned from mice”
Survey data suggest that at least as many women use e-cigs during pregnancy as tobacco cigarettes. Moreover, e-cigs deliver significant amounts of nicotine and other developmental toxicants (e.g., metals, particulate matter [PM], carbonyls) to users; there is robust evidence demonstrating an association between prenatal exposure to nicotine and adverse health, behavioral, and cognitive outcomes in the offspring. Because smoking pregnant women view e-cigs as being safer than tobacco cigarettes, they are highly-likely to use these products as another form of “smoking” during pregnancy and soon after birth. Despite the number of pregnant women who use e-cigs and the lack of available risk assessment data, there currently exist no human studies examining the health outcomes of maternal vaping during pregnancy either on the mother or offspring. Thus, laboratory studies were performed to determine the neurodevelopmental effects of early life exposure to e-cig aerosols, with and without nicotine and at a particle mass concentration and nicotine/cotinine levels relevant for human vapors. Studies revealed that perinatal exposure to e-cigs induces impaired neurodevelopment, neuro and systemic inflammation and adult later life behavioral modifications. Overall, our data indicate that exposure to e-cig aerosols, both with and without nicotine, poses a considerable risk to the developing CNS and should be considered a potential public health threat, especially early in life.
Thanks to our Guest Speakers for Spring 2018
January 11, 2018
Thank you, Natalie M. Johnson!
Professor of Immunology & Microbiology
Department of Environmental & Occupational Health
Texas A&M University School of Public Health
January 25, 2018
Thank you, Ronald Klein!
Department of Pharmacology, Toxicology & Neuroscience
Louisiana State University Health Sciences Center-Shreveport
February 8, 2018
Thank you, Michael F. Salvatore!
Institute for Healthy Aging, Center for Neuroscience Discovery
University of North Texas Health Science Center