S Khan

Science Honors Scholar Saher Khan

Saher is currently working in Dr. Evanna Gleason’s neurobiology lab at LSU. This lab focuses on studying the mechanism through which nitric oxide production in the retina leads to the release of chloride ions into the cytosol of retinal amacrine cells and subsequent effects on the sign and magnitude of postsynaptic voltage responses. Specifically, Saher performs research on the expression of the CFTR chloride transport protein in avian retinal amacrine cells. Amacrine cells are a type of interneuron in the retina, and there is pharmacological evidence suggesting that the CFTR protein is a chloride transport protein that may be involved in the aforementioned mechanism.

During the summer of 2015, she participated in LSU’s on-campus Howan Hughes Medical Institute research program. She was able to identify the expression of the CFTR gene in retinal amacrine cells, as well as colocalize it with various acidic organelles using RT-PCR and immunocytochemistry techniques. After graduation, she plans to pursue a graduate degree in the neuroscience field and hopes to use some of the research skills she has learned while at LSU for future research programs.