LSU Innovation Showcased on May 9


BATON ROUGE – Fourteen patents will be celebrated at the annual Inventorship Showcase. LSU Office of Innovation & Technology Commercial hosts the event to celebrate innovative faculty, students and staff; patents issued last fiscal year; and advances in technology commercialization at LSU. The event will be held on Tuesday, May 9, at 5:30 p.m. at the Lod Cook Alumni Center.

Three faculty members will be honored for their nationally and internationally recognized leadership in commercialization of research and artistic works. Excellence in Innovation Awards will be presented.

“A synergy around research commercialization, technology transfer, industry engagement and economic development is growing here at LSU. The Inventorship Showcase brings together all of the people who are part of this movement to celebrate and foster the spirit of innovation and entrepreneurship,” said Andrew Maas, director of the LSU Office of Innovation & Technology Commercialization.

Patents issued to LSU inventors between July 1, 2015, and June 30, 2016, include:

(Please note: LSU affiliated employees and students at the time of invention are indicated in bold.)


Vitamin E-Carnosine, or VECAR: New Antioxidant Molecule with Potential Application in Atherosclerosis
US 9,220,787
Issue Date: Dec. 29, 2015
David Spivak, Cristina M. Sabliov and Carlos E. Astete
This patent protects a new antioxidant called Vitamin E-carnosine with potential applications in treating atherosclerosis and other neurodegenerative diseases. The new antioxidant is essentially a combination of two anti-oxidants – Vitamin E, which acts as a main antioxidant and carrier; and a second antioxidant, Carnosine, which acts as a co-antioxidant and also provides protection against protein oxidation.

Curcumin Conjugates for Treating and Preventing Cancers
US 9,221,877
Issue Date: Dec. 29, 2015
Robert Hammer, Sita Aggarwal and William Hansel
The patent protects a conjugate of Curcumin, the active compound in Turmeric, a food spice commonly found in Indian curries that has been shown to have anti-carcinogenic effects. The new compound is injectable and preliminary studies in mice have demonstrated the compounds effectiveness in inhibiting growth of human prostate cancer.

Enrichment of Stem Cells from Adult Tissues
US 9,279,105
Issue Date: March 8, 2016
Gary Wise and Shaomian Yao
This patent protects a safe, simple and inexpensive method for the enrichment of stem cells from heterogeneous adult cell populations without the requirement of expensive equipment or the presence of stem cell surface markers. Using this method, adult stem cells can be purified on a large-scale without expensive equipment and without the presence of cell surface markers. By using adult stem cells, a transplant patient’s own cells may be used in tissue engineering, lessening the chances of tissue rejection.

Methods of and Devices for Capturing Circulating Tumor Cells
US 9,322,047
Issue Date: April 26, 2016
Daniel Sang-Won Park, Taehyun Park, Sudheer Rani, Michael Charles Murphy and Dimitris Nikitopoulos
This patent is for a microfluidic diagnostic medical device for capturing and quantifying circulating tumor cells from blood. The patent describes a device and methods for efficient and quick capture of target cells by flowing a sample through a novel microchannel design that contains a specialty coating and a precisely controlled velocity profile. The device has applications in cancer screening and oncology treatment strategy.

Colorimetric and Fluorometric Determination of Homocysteine and Cysteine
US 9,201,075
Issue Date: Dec. 1, 2015
Robert Strongin, Weihua Wang, Oleksandr Rusin, Nadia N. St. Luce and Jorge O. Escobedo Cordova
This patent protects a method for detecting the amino acids cysteine and homocysteine in the visible region that works at physiological concentrations, uses inexpensive and readily available reagents and attains unprecedented selectivity. This detection method may facilitate more accurate diagnosis for several diseases as high serum homocysteine levels indicate a significant risk for Alzheimer’s disease, neural tube defects and osteoporosis as well as several other serious disorders.

Detection of Nucleic Acid Sequence Differences using the Ligase Detection Reaction with Addressable Arrays
US 9,206,477
Issue Date: Dec. 8, 2015
US 9,234,241
Issue Date: Jan. 12, 2016
Robert Hammer, Francis Barany, Maria Kempe, Herman Blok, George Barany and Monib Zirvi
These patents protect methods for combining two common DNA analysis techniques to detect differences in a DNA sequence. These technologies enable large scale, reliable, cost-effective DNA analysis for forensic testing, diagnosis of genetic diseases and other genetic testing.


Apparatus and Method for Nanocomposite Sensors
US 9,099,224
Issue Date: Aug. 4, 2015
Jin-Woo Choi and Chao-Xuan Liu
This patent protects an ultra-sensitive pressure sensor made from patterned conductive nanomaterials. The use of conductive nanomaterials embedded within a flexible polymer allows for precise electrical measurements to be made as the composite layer deforms due to pressure. The sensor is useful to a variety of industries in any application where pressure needs to be measured or monitored. 

Efficient Premixing Fuel-Air Nozzle System
US 9,126,210
Issue Date: Sept. 8, 2015
Sumanta Acharya
This patent protects an improved fuel swirler nozzle that is attachable to any type of combustion chamber. Through its unique design, this micro-fuel injection swirler can reduce the amount of nitrogen oxide, or NOx, emissions and provide better chemical premixing. This increased efficiency allows for smaller, more economical combustion chambers and a more stable flame that does not blow out.

Fatigue Assessment
US 9,222,865
Issue Date: Dec. 29, 2015
Michael Khonsari and Mehdi Amiri Darehbidi
Fracture Fatigue Entropy Determination
US 9,243,985
Issue Date: Jan. 26, 2016
Michael Khonsari, Mehdi Amiri Darehbidi and Mehdi Naderi Abadi
These patents protect new diagnostic methods for determining the fatigue characteristics of materials which can benefit a variety of industries where material fatigue is a problem. “Fatigue Assessment” describes a method for evaluating fatigue of materials undergoing cyclic loading which is very useful in prolonging the life of mechanical machinery and reducing catastrophic failures. “Fracture Fatigue Entropy Determination” describes a method for preventing mechanical failures of metallic objects under cyclic loading by calculating the fracture fatigue entropy to allow for intervention before failure occurs. This is important to any industry that relies on dynamically loaded mechanical systems including aircraft, electronics, oil & gas, military, marine, automotive and structural engineering industries.


Method of CO and/or CO2 Hydrogenation using Doped Mixed-Metal Oxides
US 9,150,476
Issue Date: Oct. 6, 2015
James J. Spivey, Dushyant Shekhawat, David A. Berry, Daniel J. Haynes, Victor Abdelsayed and Mark W. Smith
This patent protects a new hydrogenation method that synthesizes higher alcohol/oxygenates from a fuel gas mixture produced from coal, natural gas, and biomass called synthesis gas, or syngas. Syngas can be used for a variety of applications including liquid transportation fuels and chemical intermediaries. The method relies on a new pyrochlore-based catalyst with the added advantages of high selectivity towards higher alcohols and higher activity toward syngas conversion at relatively lower temperatures and pressures, and high stability in the presence of a reducing environment without the need for multiple catalysts.


System and Architecture for Robust Management of Resources in a Wide-Area Network
US 9,240,955
Issue Date: Jan. 19, 2016
Supratik Mukhopadhyay and S. Sitharama Iyengar
This patent protects a system and method to allow computers on a network to reliably access, process, evaluate and take action based on information from other computers on the network. This technology allows for the network to continue functioning even in cases where portions of the network become unreliable or inaccessible. This is especially important in group communication situations such as mission critical systems and e-commerce systems.

Configurable Decoder with Applications in FPGAs
US 9,257,988
Issue Date: Feb. 9, 2016
Ramachandran Vaidyanathan and Matthew Jordan
This patent protects the MU-Decoder, which is an advanced integrated circuit hardware module that enables on-chip reconfiguration more efficiently than any decoder currently in use today. Increases in semiconductor processor speed are limited by how fast you can move data onto and out of the chip, of so-called “pin-limitation effects.” Reconfigurable chip architectures, such as those in Field Programmable Gate Arrays, or FPGAs, attempt to bypass this limitation by allowing on-chip reconfiguration of the data transfer at any given time.



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