Stephania Cormier

Stephania A. Cormier, PhD
Professor of Pediatrics
Division of Infectious Disease
University of Tennessee Health Science Center
Le Bonheur Children’s Medical Center  

LSU Superfund Research Center Program Director

LSU Superfund Research leader  Environmentally Persistent Free Radicals Alter Pulmonary Immunologic Homeostasis

 

 

Contact:

Suite 418R-CFRC
50 North Dunlap
Memphis, TN  38103
Phone: (901) 287-5329

Email: scormier@uthsc.edu     

Website: https://academic.uthsc.edu/faculty/facepage.php?netID=scormier&personnel_id=309197

 

Research interests, expertise:

  • Neonatal respiratory immunology
  • Respiratory tract viral infection
  • Inhalation exposures and host defense
  • Genome-environment interactions in airways disease. 

 

Recent Publications:

2015

Sussan, T.E., Gajghate, S., Thimmulappa, R.K., Ma, J., Kim, J.H., Sudini, K., Consolini, N., Cormier, S.A., Lomnicki, S., Hasan, F., Pekosz, A., Biswal, S. 2015. Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model. PLoS One.10(2):e0116861. Doi: 10.1371/journal.pone.0116861. PMCID: PMC4317176

 

Nau, F., Miller, J., Saravia, J., Ahlert, T., Yu, B., Happel, K. I., Cormier, S. A., & Nichols, C. D. 2015. Serotonin 5-HT2 receptor activation prevents allergic asthma in a mouse model. American Journal of Physiology - Lung Cellular and Molecular Physiology. 308(2), L191-L198. doi:10.1152/ajplung.00138.2013

 

Huang, H., Saravia, J., You, D., Shaw, A. J., & Cormier, S. A. 2015. Impaired gamma delta T cell-derived IL-17A and inflammasome activation during early respiratory syncytial virus infection in infants. Immunology and cell biology. 93(2), 126-135. doi:10.1038/icb.2014.79

 

Jaligama, S., Chen, Z., Saravia, J., Yadav, N., Lomnicki, S., Dugas, T., Cormier, S.A. 2015. Exposure to Deepwater Horizon Crude Oil Burnoff Particulate Matter Induces Pulmonary Inflammation and Alters Adaptive Immune Response. Environ. Sci. Technol. 49 (14):8769–8776. DOI: 10.1021/acs.est.5b01439. Publication Date (Web): June 26, 2015.

 

2014

Lee, G., Saravia, J., You, D., Shrestha, B., Jaligama, S., Hebert, V., Dugas. T, Cormier, S. 2014. Exposure to Combustion Generated Environmentally Persistent Free Radicals Enhances Severity of Influenza virus Infection. Part Fibre Toxicol. 11(1):57. Doi:10.1186/s12989-014-0057-1. [Epub ahead of print]

 

Schwingshackl, A., Teng, B., Makena, P., Ghosh, M., Sinclair, S.E., Luellen, C., Balasz, L., Rovnaghi, C., Bryan, R.M., Lloyd, E.E., Fitzpatrick, E., Saravia, J.S., Cormier, S.A., Waters, C.M. 2014.Deficiency of the Two-Pore-Domain Potassium Channel TREK-1 Promotes Hyperoxia-Induced Lung Injury. Crit Care Med. 42(11): 692-701.  Doi: 10.1097/CCM.0000000000000603. PMCID: PMC4199872

 

Cormier, S.A., Shrestha, B., Saravia, J., Lee, G.I., Shen, L., DeVincenzo, J.P., Kim, YI, You, D. 2014. Limited Type I IFNs and Plasmacytoid Dendritic Cells during Neonatal Respiratory Syncytial Virus Infection Permit Immunopathogenesis upon Reinfection.  J Virol. Doi 10.1128/jvi.00818-14. PMCID: PMC4136292 

 

Lomnicki, S., Gullett, B, Stöger,T., Kennedy, I., Diaz, J., Dugas, T.R., Varner, K., Carlin, D., Dellinger, B., and Cormier, S.A. 2013. Combustion By-Products and their Health Effects - Combustion Engineering and Global Health in the 21st Century: Issues and Challenges. International Journal of Toxicology. 33(1):3-13. Doi: 10.1177/1091581813519686. PMCID: PMC3944372.

  

2013

Cormier, S.A., Suter, G.W., Zheng, L., Pond, G.J. 2013. Assessing causation of the extirpation of stream macroinvertebrates by a mixture of ions. Environ Toxicol Chem, 32 (2), 277-87.

 

Kelley, M.A., Hebert, V.Y., Thibeaux, T.M., Orchard, M.A., Hasan, F., Cormier, S.A., Thevenot, P.T., Lomnicki, S.M., Varner,K.J., Dellinger, B, Latimer, B.M., Dugas, T.R. 2013. Model Combustion-Generated Particulate Matter Containing Persistent Free Radicals Redox Cycle to Produce Reactive Oxygen Species. Chem. Res. Toxicol. 26(12):1862-71. Doi: 10.1021/tx400227s.

 

Saravia, J., Lee, G.I., Lomnicki, S., Dellinger, B., and Cormier, S.A. 2013. Particulate matter containing environmentally persistent free radicals and adverse infant respiratory health effects: A review. Journal of Biochemical and Molecular Toxicology. 27(1):56-68. Doi: 10.1002/jbt.21465. PMCID: PMC3580159

 

Saravia, J.,You, D.,Thevenot, P., Lee, G. I., Shrestha, B., Lomnicki, S., Cormier, S.A. 2013. Early-life exposure to combustion-derived particulate matter causes pulmonary immunosuppression. Mucosal Immunol. Doi:10.1038/mi.2013.88. PMCID: PMC3999175

 

Thevenot, P., Saravia, J., Giammo, J., Happel, K.I., Dugas, T.R. and Cormier, S.A. 2013. Chronic Alcohol Induces M2 Polarization Enhancing Pulmonary Disease Caused by Exposure to Particulate Air Pollution. Alcoholism: Clinical and Experimental Research. 37(11): 1910-1919.Doi: 10.1111/acer.12184. PMCID: PMC3775861

 

Thevenot P.T., Saravia J., Jin N, Giaimo J.D., Chustz R.E., Mahne S., Kelley M.A., Hebert V.Y., Dellinger B., Dugas T.R., Demayo F.J., Cormier S.A. 2013. Radical-containing ultrafine particulate matter initiates epithelial-to-mesenchymal transitions in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 48:188-197. Doi: 10.1165/rcmb.2012-0052OC. PMCID: PMC3604062

 

You, D., Marr, N., Saravia, J., Shrestha, B., Lee, G.I., Turvey, S.E., Brombacher, F., Herbert, D.R., and Cormier, S.A. 2013. IL-4R alpha on CD4(+) T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. Journal of Leukocyte Biology. 93:933-942. Doi:10.1189/jlb.1012498. PMCID: PMC3656337 

 

Wang, P., You, D., Saravia, J., Shen, H., Cormier, S. 2013. Maternal Exposure to Combustion Generated PM Inhibits Pulmonary Th1 Maturation and Concomitantly Enhances Postnatal Asthma Development in Offspring. Particle and Fibre Toxicology.10(1):29. Doi:10.1186/1743-8977-10-29. PMCID: PMC3717277

 

2011

Balakrishna, S., Saravia, J., Thevenot, P., Ahlert, T., Lominiki, S., Dellinger, B., & Cormier, S.A. 2011. Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs. Part Fibre Toxicol. 8:11. Doi: 10.1186/1743-8977-8-11. PMCID:PMC3061909

 

Cormier, S.A,. Kolls, J.K. 2011. Innate IL-13 in virus-induced asthma. Nat Immunol, 12 (7), 587-8.

 

Wang P, Thevenot P, Saravia J, Ahlert T, & Cormier S. 2011. Radical Containing Particles Activate DCs and Enhance Th17 Inflammation in a Mouse Model of Asthma. Am J Respir Cell Mol Biol. 45(5):977-83. Doi: 10.1165/rcmb.2011-0001OC. PMCID:PMC3262685

 

2010 

Balakrishna, S, Saravia, J, Thevenot, P, Ahlert, T, Lominiki, S, Dellinger, B, Cormier, SA. 2010. Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs. Part Fibre Toxicol, 8, 11.

 

Cormier, S.A., You, D, Honnegowda, S. 2010. The use of a neonatal mouse model to study respiratory syncytial virus infections. Expert Rev Anti Infect Ther, 8 (12), 1371-80.

 

Fahmy, B., Ding, L., You, D., Lomnicki, S., Dellinger, B., & Cormier, S. A. 2010. In Vitro and in Vivo Assessment of Pulmonary Risk Associated with Exposure to Combustion Generated Fine Particles. Environ.Toxicology and Pharmacology. 29(2):173-82. Doi:10.1016/j.etap.2009.12.007. PMCID:PMC2848491

 

Ripple, M.J, You, D, Honnegowda, S., Giaimo, J.D., Sewell, A.B., Becnel, D.M., Cormier, SA. 2010. Immunomodulation with IL-4R alpha antisense oligonucleotide prevents respiratory syncytial virus-mediated pulmonary disease. J Immunol, 185 (8), 4804-11.

 

Walsh, M., Cormier, S.A., Varner, K., & Dellinger, B. 2010. By-Products of Thermal Treatment of Hazardous Waste: Formation and Health Effects. EM. 26-30. PMCID: PMC3368582