Stephania Cormier

Wiener Chair and Professor of Biological Sciences, Louisiana State University

LSU Superfund Research Center Program Director

LSU Superfund Research leader  Environmentally Persistent Free Radicals Alter Pulmonary Immunologic Homeostasis




1909 Freight Dock, Skip Bertman Drive

Baton Rouge, LA  70803

Phone: (225) 578-9437




Research interests, expertise:

  • Neonatal respiratory immunology
  • Respiratory tract viral infection
  • Inhalation exposures and host defense
  • Genome-environment interactions in airways disease. 


Recent Publications:


Sussan, T.E., Gajghate, S., Thimmulappa, R.K., Ma, J., Kim, J.H., Sudini, K., Consolini, N., Cormier, S.A., Lomnicki, S., Hasan, F., Pekosz, A., Biswal, S. 2015. Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model. PLoS One.10(2):e0116861. Doi: 10.1371/journal.pone.0116861. PMCID: PMC4317176


Nau, F., Miller, J., Saravia, J., Ahlert, T., Yu, B., Happel, K. I., Cormier, S. A., & Nichols, C. D. 2015. Serotonin 5-HT2 receptor activation prevents allergic asthma in a mouse model. American Journal of Physiology - Lung Cellular and Molecular Physiology. 308(2), L191-L198. doi:10.1152/ajplung.00138.2013


Huang, H., Saravia, J., You, D., Shaw, A. J., & Cormier, S. A. 2015. Impaired gamma delta T cell-derived IL-17A and inflammasome activation during early respiratory syncytial virus infection in infants. Immunology and cell biology. 93(2), 126-135. doi:10.1038/icb.2014.79


Jaligama, S., Chen, Z., Saravia, J., Yadav, N., Lomnicki, S., Dugas, T., Cormier, S.A. 2015. Exposure to Deepwater Horizon Crude Oil Burnoff Particulate Matter Induces Pulmonary Inflammation and Alters Adaptive Immune Response. Environ. Sci. Technol. 49 (14):8769–8776. DOI: 10.1021/acs.est.5b01439. Publication Date (Web): June 26, 2015.



Lee, G., Saravia, J., You, D., Shrestha, B., Jaligama, S., Hebert, V., Dugas. T, Cormier, S. 2014. Exposure to Combustion Generated Environmentally Persistent Free Radicals Enhances Severity of Influenza virus Infection. Part Fibre Toxicol. 11(1):57. Doi:10.1186/s12989-014-0057-1. [Epub ahead of print]


Schwingshackl, A., Teng, B., Makena, P., Ghosh, M., Sinclair, S.E., Luellen, C., Balasz, L., Rovnaghi, C., Bryan, R.M., Lloyd, E.E., Fitzpatrick, E., Saravia, J.S., Cormier, S.A., Waters, C.M. 2014.Deficiency of the Two-Pore-Domain Potassium Channel TREK-1 Promotes Hyperoxia-Induced Lung Injury. Crit Care Med. 42(11): 692-701.  Doi: 10.1097/CCM.0000000000000603. PMCID: PMC4199872


Cormier, S.A., Shrestha, B., Saravia, J., Lee, G.I., Shen, L., DeVincenzo, J.P., Kim, YI, You, D. 2014. Limited Type I IFNs and Plasmacytoid Dendritic Cells during Neonatal Respiratory Syncytial Virus Infection Permit Immunopathogenesis upon Reinfection.  J Virol. Doi 10.1128/jvi.00818-14. PMCID: PMC4136292 


Lomnicki, S., Gullett, B, Stöger,T., Kennedy, I., Diaz, J., Dugas, T.R., Varner, K., Carlin, D., Dellinger, B., and Cormier, S.A. 2013. Combustion By-Products and their Health Effects - Combustion Engineering and Global Health in the 21st Century: Issues and Challenges. International Journal of Toxicology. 33(1):3-13. Doi: 10.1177/1091581813519686. PMCID: PMC3944372.



Cormier, S.A., Suter, G.W., Zheng, L., Pond, G.J. 2013. Assessing causation of the extirpation of stream macroinvertebrates by a mixture of ions. Environ Toxicol Chem, 32 (2), 277-87.


Kelley, M.A., Hebert, V.Y., Thibeaux, T.M., Orchard, M.A., Hasan, F., Cormier, S.A., Thevenot, P.T., Lomnicki, S.M., Varner,K.J., Dellinger, B, Latimer, B.M., Dugas, T.R. 2013. Model Combustion-Generated Particulate Matter Containing Persistent Free Radicals Redox Cycle to Produce Reactive Oxygen Species. Chem. Res. Toxicol. 26(12):1862-71. Doi: 10.1021/tx400227s.


Saravia, J., Lee, G.I., Lomnicki, S., Dellinger, B., and Cormier, S.A. 2013. Particulate matter containing environmentally persistent free radicals and adverse infant respiratory health effects: A review. Journal of Biochemical and Molecular Toxicology. 27(1):56-68. Doi: 10.1002/jbt.21465. PMCID: PMC3580159


Saravia, J.,You, D.,Thevenot, P., Lee, G. I., Shrestha, B., Lomnicki, S., Cormier, S.A. 2013. Early-life exposure to combustion-derived particulate matter causes pulmonary immunosuppression. Mucosal Immunol. Doi:10.1038/mi.2013.88. PMCID: PMC3999175


Thevenot, P., Saravia, J., Giammo, J., Happel, K.I., Dugas, T.R. and Cormier, S.A. 2013. Chronic Alcohol Induces M2 Polarization Enhancing Pulmonary Disease Caused by Exposure to Particulate Air Pollution. Alcoholism: Clinical and Experimental Research. 37(11): 1910-1919.Doi: 10.1111/acer.12184. PMCID: PMC3775861


Thevenot P.T., Saravia J., Jin N, Giaimo J.D., Chustz R.E., Mahne S., Kelley M.A., Hebert V.Y., Dellinger B., Dugas T.R., Demayo F.J., Cormier S.A. 2013. Radical-containing ultrafine particulate matter initiates epithelial-to-mesenchymal transitions in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 48:188-197. Doi: 10.1165/rcmb.2012-0052OC. PMCID: PMC3604062


You, D., Marr, N., Saravia, J., Shrestha, B., Lee, G.I., Turvey, S.E., Brombacher, F., Herbert, D.R., and Cormier, S.A. 2013. IL-4R alpha on CD4(+) T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. Journal of Leukocyte Biology. 93:933-942. Doi:10.1189/jlb.1012498. PMCID: PMC3656337 


Wang, P., You, D., Saravia, J., Shen, H., Cormier, S. 2013. Maternal Exposure to Combustion Generated PM Inhibits Pulmonary Th1 Maturation and Concomitantly Enhances Postnatal Asthma Development in Offspring. Particle and Fibre Toxicology.10(1):29. Doi:10.1186/1743-8977-10-29. PMCID: PMC3717277



Balakrishna, S., Saravia, J., Thevenot, P., Ahlert, T., Lominiki, S., Dellinger, B., & Cormier, S.A. 2011. Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs. Part Fibre Toxicol. 8:11. Doi: 10.1186/1743-8977-8-11. PMCID:PMC3061909


Cormier, S.A,. Kolls, J.K. 2011. Innate IL-13 in virus-induced asthma. Nat Immunol, 12 (7), 587-8.


Wang P, Thevenot P, Saravia J, Ahlert T, & Cormier S. 2011. Radical Containing Particles Activate DCs and Enhance Th17 Inflammation in a Mouse Model of Asthma. Am J Respir Cell Mol Biol. 45(5):977-83. Doi: 10.1165/rcmb.2011-0001OC. PMCID:PMC3262685



Balakrishna, S, Saravia, J, Thevenot, P, Ahlert, T, Lominiki, S, Dellinger, B, Cormier, SA. 2010. Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs. Part Fibre Toxicol, 8, 11.


Cormier, S.A., You, D, Honnegowda, S. 2010. The use of a neonatal mouse model to study respiratory syncytial virus infections. Expert Rev Anti Infect Ther, 8 (12), 1371-80.


Fahmy, B., Ding, L., You, D., Lomnicki, S., Dellinger, B., & Cormier, S. A. 2010. In Vitro and in Vivo Assessment of Pulmonary Risk Associated with Exposure to Combustion Generated Fine Particles. Environ.Toxicology and Pharmacology. 29(2):173-82. Doi:10.1016/j.etap.2009.12.007. PMCID:PMC2848491


Ripple, M.J, You, D, Honnegowda, S., Giaimo, J.D., Sewell, A.B., Becnel, D.M., Cormier, SA. 2010. Immunomodulation with IL-4R alpha antisense oligonucleotide prevents respiratory syncytial virus-mediated pulmonary disease. J Immunol, 185 (8), 4804-11.


Walsh, M., Cormier, S.A., Varner, K., & Dellinger, B. 2010. By-Products of Thermal Treatment of Hazardous Waste: Formation and Health Effects. EM. 26-30. PMCID: PMC3368582