Doug Gilman

Doug Gilman

gilman

Bachelor's Degree(s): Harvey Mudd College, 1989
PhD: The Pennsylvania State University, 1994
PostDoc: University of California, Davis, 1994-1997

Area of Interest
Our research is centered on the development of new bioanalytical chemistry techniques and their application to address research problems at the frontiers of biochemistry and biomedicine.  Our adventures in pursuit of new bioanalytical measurement methods lead us in exciting and often unexpected scientific directions.  One current project focuses on the development and application of capillary electrophoretic assays for studying enzyme inhibition.  Another current research interest is the development of separation and detection methods for studying protein aggregation related to diseases such as Alzheimer’s Disease, Huntington’s Disease and Parkinson’s disease.  We also are interested in fundamental experimental studies of electroosmotic flow and immobilization of magnetic particles in microfluidic systems. 

Awards & Honors
Governing Board Chair, Federation of Analytical Chemistry and Spectroscopy Societies, 2010-2011

Sigma Xi Distinguished Lecturer, 2010-2012

Society for Applied Spectroscopy Tour Speaker, 2007

University of Tennessee Award for Professional Promise in Research and Creative Achievement, 2002

NSF CAREER Award, 2001

NRSA Postdoctoral Fellow (NIEHS), 1995-1997


Selected Publications
Picou, R. A.; Schrum, D. P.; Ku, G.; Kheterpal, I.; Gilman S. D. Separation and Detection of Individual A-Beta Aggregates by Capillary Electrophoresis.Anal. Bioch. 2012, 425, 104-112.


Henken, R. L.; Chantiwas, R.; Gilman, S. D. Influence of Immobilized Biomolecules on Magnetic Bead Plug Formation and Retention in Capillary Electrophoresis. Electrophoresis, 2012, 33, 827-833.


Meades, Jr. G.; Henken, R. L.; Waldrop, G. L.; Rahman, Md. M.; Gilman, S. D.; Kamatou, G. P. P.; Viljoen, A. M.; Gibbons, S. Constituents of Cinnamon Inhibit Bacterial Acetyl CoA Carboxylase. Planta Med. 2010, 76, 1570-1575.


Picou, R.; Moses, J. P.; Wellman, A. D.; Kheterpal, I.; Gilman, S. D. Analysis of Monomeric A-Beta (1-40) Peptide by Capillary Electrophoresis. Analyst,2010, 135, 1631-1635.


Yan, X.; Gilman, S. D. Improved Peak Capacity of CE Separations of Enzyme Inhibitors with Activity-Based Detection Using Magnetic Bead Microreactors. Electrophoresis, 2010, 31, 346-354.


Rezenom, Y. H.; Wellman, A. D.; Tilstra, L.; Medley, C. D.; Gilman, S. D. Separation and Detection of Individual Submicron Particles by Capillary Electrophoresis with Laser-Light Scattering Detection. Analyst, 2007, 132, 1215-1222.


Pittman, J. L.; Henry, C. S.; Gilman, S. D..  Experimental Studies of Electroosmotic Flow Dynamics During Current Monitoring Experiments.  Anal. Chem., 2003, 75, 361-370.


Pittman, J. L.; Henry, C. S.; Gilman, S. D..  Experimental Studies of Electroosmotic Flow Dynamics During Current Monitoring Experiments.  Anal. Chem., 2003, 75, 361-370.


Pittman, J. L.; Gessner, H. J.; Frederick, K. A.; Raby, E. M.; Batts, J. B.; Gilman, S. D..  Experimental Studies of Electroosmotic Flow Dynamics During Sample Stacking for Capillary Electrophoresis.  Anal. Chem., 2003, 75, 3199-3206.


Whisnant, A. R.; Gilman, S. D..  Studies of Reversible Inhibition, Irreversible Inhibition and Activation of Alkaline Phosphatase by Capillary Electrophoresis.  Anal. Biochem., 2002, 307, 226-234.